๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Effect of adherence to plastic on peripheral blood monocyte and alveolar macrophage chemiluminescence

โœ Scribed by de Sole, P. ;Fresu, R. ;Frigieri, L. ;Pagliari, G. ;de Simone, C. ;Guerriero, C.


Publisher
John Wiley and Sons
Year
1993
Weight
388 KB
Volume
8
Category
Article
ISSN
0884-3996

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โœฆ Synopsis


The chemiluminescence of peripheral blood monocytes and alveolar macrophages was determined in the presence of luminol and lucigenin, either before or after the cell adherence to the luminometer curvettes. In the case of monocytes, cell adherence induces an increase of luminol-dependent chemiluminescence and has almost no effect on the lucigenin-dependent chemiluminescence. However, it shows a strong inhibition of the lucigenin-dependent chemiluminescence and almost no effect on luminol-dependent chemiluminescence, in the case of alveolar macrophages. These results show that adhesion t o plastic alters the metabolic burst of both monocytes and alveolar macrophages. Although the mechanisms are poorly understood, they seem to be related t o the modifications that take place during the differentiation of peripheral monocytes t o alveolar macrophages.


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