𝔖 Bobbio Scriptorium
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300 Sensitivity of NS3 serine proteases from various hepatitis C virus genotypes to the antiviral compound BILN 2061

✍ Scribed by Diane Thibeault; Christiane Bousquet; Rock Gingras; Lisette Lagacé; Roger Maurice; Peter W. White; Daniel Lamarre


Book ID
119530209
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
150 KB
Volume
38
Category
Article
ISSN
0270-9139

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## Abstract The virally encoded serine protease NS3/NS4A is essential to the life cycle of the hepatitis C virus (HCV), an important human pathogen causing chronic hepatitis, cirrhosis of the liver, and hepatocellular carcinoma. Until very recently, the design of inhibitors for the HCV NS3 protease