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3-Phosphoinositide-dependent protein kinase-1/Akt signalling and inhibition in a canine prostate carcinoma cell line

✍ Scribed by F. J. Alvarez; S. Murahari; C. G. Couto; T. J. Rosol; S. K. Kulp; C.-S. Chen; W. C. Kisseberth


Book ID
111220066
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
322 KB
Volume
5
Category
Article
ISSN
1476-5810

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## Abstract The androgen receptor (AR) is a ligand‐dependent transcription factor belonging to the steroid hormone receptor superfamily. Under normal conditions, in the absence of a ligand, the AR is localized to the cytoplasm and is actively transported into the nucleus upon binding of androgens.