✦ LIBER ✦

3-Phenyl-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]indole-2-carbonitrile, a potent inhibitor of prostaglandin synthetase and of platelet aggregation

✍ Scribed by Fahrenholtz, Kenneth E.; Silverzweig, Mary Z.; Germane, Nicholas; Crowley, Herman J.; Simko, Beverly A.; Dalton, Colin

Book ID: 126417025
Publisher: American Chemical Society
Year: 1979
Tongue: English
Weight: 841 KB
Volume: 22
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00194a012

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

6-Methyl-1,2,3,5-tetrahydroimidazo[2,1-b

6-Methyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-one, a potent inhibitor of ADP-induced platelet aggregation

✍ Beverung, W. N.; Partyka, R. A. 📂 Article 📅 1975 🏛 American Chemical Society 🌐 English ⚖ 261 KB

An efficient and scalable synthesis of (

An efficient and scalable synthesis of (2R,αS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol: A potent CETP inhibitor

✍ Aihua Wang; Yan Zhang; Songfeng Lu; William V. Murray; Gee-Hong Kuo 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 140 KB

## Abstract magnified image An efficient and scalable synthesis of the potent CETP inhibitor, (2__R__,α__S__)‐3,4‐dihydro‐2‐[3‐(1,1,2,2‐tetrafluoroethoxy)phenyl]‐5‐[3‐(trifluoromethoxy)phenyl]‐α‐(trifluoromethyl)‐1(2__H__)‐quinolineethanol 1, is described. One of the important intermediates, tetrah

ChemInform Abstract: An Efficient and Sc

ChemInform Abstract: An Efficient and Scalable Synthesis of (2R,αS)-3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5- [3-(trifluoromethoxy)phenyl] -α-(trifluoromethyl)-1(2H)-quinolineethanol: A Potent CETP Inhibitor.

✍ Aihua Wang; Yan Zhang; Songfeng Lu; William V. Murray; Gee-Hong Kuo 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Design, Synthesis, and Biological Evalua

Design, Synthesis, and Biological Evaluation of (2R,αS)-3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol as Potent and Orally Active Cholesteryl Ester Transfer Protein Inhibitor

✍ Rano, Thomas; Pelton, Patricia; Demarest, Keith T.; Gibbs, Alan C.; Murray, Will 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 787 KB

Inhibitors of platelet aggregation. 1. 5

Inhibitors of platelet aggregation. 1. 5,10-Dihydro-3-(phenyl, thienyl, and furyl)thiazolo[3,2-b][2,4]benzodiazepines and related compounds

✍ Elslager, Edward F.; McLean, J. R.; Perricone, Salvatore C.; Potoczak, Doris; Ve 📂 Article 📅 1971 🏛 American Chemical Society 🌐 English ⚖ 569 KB

Reactions of ethyl 1-benzylidene-7a-hydr

Reactions of ethyl 1-benzylidene-7a-hydroxy-4-phenyl-6-oxooctahydro-1H-indene-5-carboxylate and ethyl 5-benzylidene-4a-hydroxy-1-phenyl-3-oxodecahydronaphthalene-2-carboxylate with 1,2,4-triazol-3-amine. Synthesis of substituted triazoloquinazolines

✍ T. V. Gulai, A. G. Golikov 📂 Article 📅 2012 🏛 SP MAIK Nauka/Interperiodica 🌐 English ⚖ 179 KB