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3-Methyl-8-(substituted phenyl)-pteridine-2,4(3H,8H)-diones as Potential Antimalarials

✍ Scribed by Halladay, PK; Cowden, WB

Book ID: 120662516
Publisher: Commonwealth Scientific and Industrial Research Organisation Publishing
Year: 1990
Tongue: English
Weight: 256 KB
Volume: 43
Category: Article
ISSN: 0004-9425
DOI: 10.1071/CH9901449

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## Abstract The reactions of 5,6‐diaminopyrimidin‐4(3__H__)‐one derivatives 1a‐h, with dimethyl acetylenedicarboxylate are discussed in this paper. 6‐Amino‐5‐(__E__)(1′,2′‐dicarbomethoxyvinyl)aminopyrimidines, 2, and 6‐(methylenecarbomethoxy)pteridinones, 3, have been obtained as main the products,