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3-(methoxycarbonyl)-amino-β-carboline, a selective antagonist of the sedative effects of benzodiazepines

✍ Scribed by Lia Prado de Carvalho; Patrice Venault; Marie-Claude Potier; Robert H. Dodd; ChloëL. Brown; Georges Chapouthier; Jean Rossier


Book ID
115880094
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
768 KB
Volume
129
Category
Article
ISSN
0014-2999

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Evaluation of the β-carboline ZK 93 426
✍ Leif H. Jensen; Erling N. Petersen; Claus Braestrup; Tage Honoré; Wolfgang Kehr; 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 868 KB

We describe here biochemical and pharmacological effects of the beta-carboline ZK 93426 was compared with Ro 15-1788 and CGS 8216, two compounds previously described as BZ receptor antagonists. Certain effects of ZK 93426, Ro 15-1788 and CGS 8216 were quite similar (e.g., 3H-FNM displacement, "GABA