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3-Hydroxyquinuclidinium derivatives: synthesis of compounds and inhibition of acetylcholinesterase

✍ Scribed by Elsa Reiner; Mira Škrinjarić-Špoljar; Sanja Dunaj; Vera Simeon-Rudolf; Ines Primožič; Srðanka Tomić


Book ID
114009704
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
107 KB
Volume
119-120
Category
Article
ISSN
0009-2797

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✍ Roberto J. Falkenstein; Germán G. Gornalusse; Dr Clara Peña 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

## Abstract Fasciculins are peptides isolated from mamba (__Dendroaspis__) venoms which exert their toxic action by inhibiting acetylcholinesterase (AChE). They contain a characteristic triple stranded antiparallel β‐sheet formed by residues 22–27, 34–39 and 48–53. A chimeric peptide named Fas‐C, e