Synthesis and In Vitro Antitumor Activit
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Schott, Herbert ;Ludwig, Peter S. ;Gansauge, Frank ;Gansauge, Susanne ;Schwenden
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Article
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1997
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John Wiley and Sons
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English
⚖ 549 KB
## Abstract The new amphiphilic dinucleoside phosphate, 2′‐deoxy‐5‐fluorouridylyl‐(3′→5′)‐2′‐deoxy‐5‐fluoro‐__N__^4^‐octadecylcytidine (4) was synthesized on a gram scale, using the phosphotriester method, starting from the cytostatic drug 2′‐deoxy‐5‐fluorouridine (5FdU) and 2′‐deoxy‐5‐fluoro‐__N__