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3-D microwell culture of human embryonic stem cells

✍ Scribed by Jeffrey C. Mohr; Juan J. de Pablo; Sean P. Palecek

Book ID: 108069729
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 893 KB
Volume: 27
Category: Article
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2006.07.012

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## Abstract Human embryonic stem cells (hESCs) during long‐term culture acquire chromosomal changes similar to those occurring in tumorigenesis. This was raised concerns about the progression from hESCs to malignant cells. This study aimed to investigate the changes in chromosomes, cell phenotype,