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3-Allyl-4-aryl-1,3,4-oxa(and thia)diazolidine-2,5-diones and thio analogs via a facile polyhetero-Claisen rearrangement

โœ Scribed by Pilgram, Kurt H.; Skiles, Richard D.; Kleier, Daniel A.


Book ID
126053895
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
490 KB
Volume
53
Category
Article
ISSN
0022-3263

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Facile synthesis of 4-alkoxycarbonylisoq
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## Abstract magnified image A series of 4โ€methoxycarbonylisoquinolineโ€1,3โ€diones was obtained from homophthalic acid in four steps. The key step was the quantitative and rapid alkaline cyclization of 2โ€methoxycarbonylโ€2โ€(2โ€methoxycarbonylphenyl) acetamides. Homologation easily afforded in the same