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(2S*,3R*,4S*,5R*)-3-(S*-1-Benzyl­oxy­ethyl)-4-methyl-4-nitro-5-phenyl­proline methyl ester

✍ Scribed by Linden, Anthony ;Ayerbe, Mirari ;Arrieta, Ana ;Zubia, Aizpea ;Vivanco, Silvia ;Erquicia, Edurne ;Aldaba, Eneko ;Cossío, Fernando P. ;Lecea, Begoña

Publisher
International Union of Crystallography
Year
2001
Tongue
English
Weight
273 KB
Volume
57
Category
Article
ISSN
1600-5368

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✦ Synopsis

At 173 K, the ®ve-membered ring of the title compound, C 22 H 26 N 2 O 5 , has an envelope conformation. The amine group is involved in both intramolecular and intermolecular hydrogen bonds, the latter linking the molecules into centrosymmetric dimers.

Experimental

The title compound was prepared according to the procedure of Ayerbe et al. (1998). The reaction gave a mixture of three diastereoisomers, (3a±c), in the proportions 59:29:12, which were separated

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