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2D and 3D Quantitative Structure Activity Relationship studies of Human Microsomal Epoxide Hydrolase Inhibitors

✍ Scribed by Maryam Hamzeh-Mivehroud; Siavoush Dastmalchi; Nasim Ahmadzadehnia

Book ID: 118430951
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 53 KB
Volume: 44
Category: Article
ISSN: 0009-9120
DOI: 10.1016/j.clinbiochem.2011.08.246

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## Abstract A quantitative structure activity relationship (QSAR) analysis was performed on the $K\_i $ values of a series of fatty acid amide hydrolase (FAAH) inhibitors. Six molecular descriptors selected by CODESSA software were used as inputs to perform heuristic method (HM) and support vector