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296 PDGFβ AND TGFβ1 STIMULATES HEPATIC STELLATE CELLS THROUGH C-ABL ACTIVATION

✍ Scribed by C. Candelaresi; S. Saccomanno; F. Marra; S. De Minicis; L. Agostinelli; A. Benedetti; G. Svegliati-Baroni

Book ID: 117377306
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 49 KB
Volume: 50
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(09)60298-1

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## Abstract ## Background/aims Transforming growth factor β (TGFβ1) is considered the key mediator in the process of liver fibrosis. The purpose of this investigation was to evaluate the activity of ribozymes against TGFβ1 in a cell‐free system and activated hepatic stellate cells (HSCs), and anti