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Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected withSchistosoma japonicum

✍ Scribed by Zhu, Dandan; He, Xue; Duan, Yinong; Chen, Jinling; Wang, Jianxin; Sun, Xiaolei; Qian, Hongyan; Feng, Jinrong; Sun, Wei; Xu, Feifan; Zhang, Lingbo


Book ID
125403398
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
419 KB
Volume
7
Category
Article
ISSN
1756-3305

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## Abstract ## Background/aims Transforming growth factor β (TGFβ1) is considered the key mediator in the process of liver fibrosis. The purpose of this investigation was to evaluate the activity of ribozymes against TGFβ1 in a cell‐free system and activated hepatic stellate cells (HSCs), and anti