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29 Nasal Delivery of Anti-CD3 Antibody Suppresses Murine Lupus by Inducing IL-10 Producing Foxp3+CD4+CD25−LAP+ Regulatory T Cells

✍ Scribed by Henry Yim Wu; Howard Weiner


Book ID
113539899
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
51 KB
Volume
123
Category
Article
ISSN
1090-2341

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a