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2642. Possible biochemical basis for carbon tetrachloride carcinogenicity…: Rocchi, P., Prodi, G., Grilli, S. & Ferreri, A. M. (1973). In vivo and in vitro binding of carbon tetrachloride with nucleic acids and proteins in rat and mouse liver. Int. J. Cancer11, 419

Book ID
114025876
Publisher
Elsevier Science
Year
1973
Weight
78 KB
Volume
11
Category
Article
ISSN
0015-6264

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In vivo and in vitro binding of carbon t
In vivo and in vitro binding of carbon tetrachloride with nucleic acids and proteins in rat and mouse liver
✍ P. Rocchi; G. Prodi; S. Grilli; A. M. Ferreri 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 French ⚖ 437 KB 👁 1 views

## Abstract ^14^C‐labelled carbon tetrachloride binds __in vivo__ to DNA of mouse liver and to ^r^RNA of rat liver if the animals have been pretreated with 3‐methylcholanthrene. A noticeable amount of radioactivity is also observed in liver proteins. In vitro carbon tetrachloride is activated by mi