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264 Strong Melan-A/MART-1 specific CD8+ T cell responses to peptide vaccination in young melanoma patients

โœ Scribed by D. Speiser; D. Lienard; V. Rubio-Godoy; E. Devevre; A.M. Krieg; J.-C. Cerottini; P. Romero

Book ID
118621447
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
147 KB
Volume
2
Category
Article
ISSN
1359-6349

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## Abstract MHC class I tetramers containing peptide epitopes are sensitive tools for detecting antigenโ€specific CD8^+^ Tโ€cell responses. We demonstrate here that binding of HLAโ€A2 tetramers to CD8^+^ T cells specific for the melanomaโ€associated antigen Melanโ€A/MARTโ€1 can be fineโ€tuned by altering