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Peptide vaccination elicits leukemia-associated antigen-specific cytotoxic CD8+ T-cell responses in patients with chronic lymphocytic leukemia

✍ Scribed by Giannopoulos, K; Dmoszynska, A; Kowal, M; Rolinski, J; Gostick, E; Price, D A; Greiner, J; Rojewski, M; Stilgenbauer, S; Döhner, H

Book ID: 109887325
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 696 KB
Volume: 24
Category: Article
ISSN: 0887-6924
DOI: 10.1038/leu.2010.29

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## BACKGROUND. Most strategies in cancer immunotherapy are aimed at the induction of a strong cellular immune response against the tumor. Particularly, CD8 + T lymphocytes have been proven in multiple animal models to be critical for the eradication of solid tumors. METHODS. We used a population o