๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

26 Obstructive cholestasis results in down-regulation and functional impairment of the organic cation transporter 1 (OCT1) in rat

โœ Scribed by Gerald U. Denk; Carol J. Soroka; Albert Mennone; Hermann Koepsell; Ulrich Beuers; James L. Boyer

Book ID
119529935
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
131 KB
Volume
38
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Down-regulation of the organic cation tr
Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis
โœ Gerald U. Denk; Carol J. Soroka; Albert Mennone; Hermann Koepsell; Ulrich Beuers ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 200 KB

The liver plays a major role in biotransformation and elimination of various therapeutic agents and xenobiotics, many of which are organic cations and substrates of the organic cation transporter 1 (Oct1, Slc22a1). Oct1 is expressed at the basolateral membranes of hepatocytes and proximal renal tubu