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255Residual DNA double-strand breaks and cellular radiosensitivity of 12 normal human fibroblasts

✍ Scribed by Ingo Brammer; Ekkehard Dikomey; Jørgen Johansen; Søren M. Bentzen; Jens Overgaard

Book ID
119521571
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
121 KB
Volume
40
Category
Article
ISSN
0167-8140

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## Abstract DNA double‐strand breaks (DSBs) are the most hazardous lesions arising in the genome of eukaryotic organisms, and yet occur normally during DNA replication, meiosis, and immune system development. The efficient repair of DSBs is crucial in maintaining genomic integrity, cellular viabili