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251 Histone deacetylase inhibition — a promising anticancer therapeutic strategy

✍ Scribed by P. Atadja; M. Hsu; P. Kwon; R. Pili; K. Bhalla; A. Wood

Book ID
118621434
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
141 KB
Volume
2
Category
Article
ISSN
1359-6349

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## Abstract Aberrant epigenetic regulation of gene expression contributes to tumor initiation and progression. Studies from a plethora of hematologic and solid tumors support the use of histone deacetylase inhibitors (HDACi) as potent anticancer agents. The mechanism(s) of HDACi‐induced cancer grow