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251 CASPASE-DEPENDENT INTRINSIC APOPTOSIS IN GROWTH INHIBITION OF HEPATOMA CELLS INDUCED BY CYCLOOXYGENASE-2 INHIBITOR

✍ Scribed by I.H. Song; E.Y. Kim; K.C. Shin; H.D. Shin; S.Y. Yun; S.B. Kim

Book ID
117377261
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
52 KB
Volume
50
Category
Article
ISSN
0168-8278

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## Abstract Many tumors constitutively express high levels of the inducible form of proinflammatory enzyme, cyclooxygenase‐2 (COX‐2). Increased COX‐2 expression is associated with tumor cell resistance to many cytotoxic chemotherapy drugs. Furthermore, increased resistance to cytotoxic antitumor dr