✦ LIBER ✦

2,5-S,S-Dicysteinyldopa: A new amino acid in the eye of the gar and its enzymic synthesis

✍ Scribed by Shosuke Ito; J.A.C. Nicol

Publisher: Elsevier Science
Year: 1975
Tongue: French
Weight: 176 KB
Volume: 16
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)91427-8

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✦ Synopsis

In the course of a study of reflecting materials in fish eyesl, we have isolated from the alligator gar Lepisosteus spatula a new amino acid whose structure has been established as 2,5-S,S-dicysteinyldopa (Ia). An acid extract (lM HCl) of 50 eyes was passed on to a Dowex-SOW x4 (H+ form) column and, after washing with 1M HCl, the amino acid was eluted with 6M HCl, and then chromatographed on Sephadex LH-20, using MeOH:lM HCl 19:l as eluent. The amino acid was further purified by paper chromatography in n-PrOH:lM HCl 3:2 and converted to the formate by passing through a Dowex-2 x8 (formate form) column. Chromatography on

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