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25-Hydroxyvitamin D-1α Hydroxylase: Studies in Mouse Models and Implications for Human Disease

✍ Scribed by David Goltzman

Book ID
107568753
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
280 KB
Volume
7
Category
Article
ISSN
1534-8644

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✍ Tai C. Chen; Lilin Wang; Lyman W. Whitlatch; John N. Flanagan; Michael F. Holick 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract Evidence suggests that vitamin D may have a protective role for prostate cancer. 1α,25‐Dihydroxyvitamin D [1α,25(OH)~2~D] inhibits growth and induces differentiation of prostate cells. 25‐Hydroxyvitamin D‐1α‐hydroxylase [1α‐OHase], the enzyme that is responsible for the synthesis of 1α,