2,5-Dimethyl-7-phenylsulfonyl-5,6-dihydroindolo[2,3-c]benzazepin-12-one
✍ Scribed by Ravishankar, T. ;Chinnakali, K. ;Arumugam, N. ;Srinivasan, P. C. ;Usman, Anwar ;Fun, Hoong-Kun
- Publisher
- International Union of Crystallography
- Year
- 2005
- Tongue
- English
- Weight
- 193 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1600-5368
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## Synthesis of 7,12-Dihydro-indo~o[3~[l]benzazepin-6-(~~nes and gll-Dihydr~.thieno-[3'3':~]~zepino[qS-b]indol-5(4H)-one The title compounds 4 and 6 were prepared by Fischer indole synthesis. 4a is substituted in 10-position by reaction with bromine in glacial acetic acid. A fast ring inversion is
The title compound, C 12 H 14 N 6 , was synthesized via cyclocondensation of 5-guanidino-3-phenyl-1,2,4-triazole with acetone. Only one tautomeric form with the NH H atom vicinal to the methyl groups was observed in the crystal structure. The triazine ring adopts a flattened half-boat conformation.
## Abstract A novel synthesis of substituted thieno[3,2‐__c__]azepinones is described. This new approach uses 5,5‐dimethyl‐1,3‐cyclohexanedione (dimedone) as the starting material. Oxime intermediates are obtained in three steps from the aforementioned diketone. Using these intermediates, the title