14C]AZQ (2-4 mg/m 2, 100 200 mCi) was administered at varying times to five patients undergoing surgical resection of intracerebral tumors. Plasma, cerebrospinal fluid (CSF), edematous brain, and tumor specimens were obtained during surgery and the concentration of AZQ was determined radiochemically
2,5-Diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone II: Isolation and characterization of degradation products
✍ Scribed by G. K. Poochikian; J. A. Kelley
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 779 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0022-3549
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## Abstract In the course of saponification experiments with bis(2‐cyanoethyl) 2,6‐dimethyl‐4‐(2‐nitrophenyl)‐1,4‐dihydro‐3,5‐pyridinedicarboxylate (**1**), an analogue of the calcium channel blocker nifedipine, three unexpected degradation products were isolated. The compounds were identified as 3
triphenylphosphanimino)tetrazolo [5,1-a][1,3,5]tri-An improved crystal structure for 2,4,6-triazido-1,3,5-triazine (2) was determined and for the first time a 14 N-NMR azine (1) was synthesized by reaction of cyanuric azide with triphenylphosphane. 1 is characterized by X-ray structural spectrum was