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248 Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo

โœ Scribed by A. Hrzenjak; F. Moinfar; M.L. Kremser; B. Strohmeier; E. Petru; K. Zatloukal; H. Denk


Book ID
119602035
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
46 KB
Volume
8
Category
Article
ISSN
1359-6349

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Histone deacetylase inhibitors (HDACi) suppress cancer cell growth, inflammation, and bone resorption. The aim of this study was to determine the effect of inhibitors of different HDAC classes on human osteoclast activity in vitro. Human osteoclasts generated from blood mononuclear cells stimulated