✦ LIBER ✦

2,4,6-Trinitrotoluene inhibits endothelial nitric oxide synthase activity and elevates blood pressure in rats

✍ Scribed by Yang Sun; Motoyuki Iemitsu; Nobutake Shimojo; Takashi Miyauchi; Masahiro Amamiya; Daigo Sumi; Toshio Hayashi; Guifan Sun; Nobuhiro Shimojo; Yoshito Kumagai

Publisher: Springer-Verlag
Year: 2005
Tongue: English
Weight: 254 KB
Volume: 79
Category: Article
ISSN: 0340-5761
DOI: 10.1007/s00204-005-0003-y

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Cyclosporin-A Inhibits Constitutive Nitr

Cyclosporin-A Inhibits Constitutive Nitric Oxide Synthase Activity and Neuronal and Endothelial Nitric Oxide Synthase Expressions after Spinal Cord Injury in Rats

✍ Araceli Diaz-Ruiz; Paula Vergara; Francisca Perez-Severiano; Jose Segovia; Gabri 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 231 KB

Atorvastatin lowers portal pressure in c

Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase

✍ Jonel Trebicka; Martin Hennenberg; Wim Laleman; Nataliya Shelest; Erwin Biecker; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 685 KB

In cirrhosis, increased RhoA/Rho-kinase signaling and decreased nitric oxide (NO) availability contribute to increased intrahepatic resistance and portal hypertension. Hepatic stellate cells (HSCs) regulate intrahepatic resistance. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins)

Elevated glomerular and blood mononuclea

Elevated glomerular and blood mononuclear lymphocyte nitric oxide production in rats with chronic bile duct ligation: Role of inducible nitric oxide synthase activation

✍ M Criado; O Flores; M C Ortiz; F Hidalgo; A M Rodriguez-Lopez; N Eleno; N M Atuc 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 690 KB

Recent work indicates that nitric oxide (NO) plays an important role in the systemic and renal alterations of cirrhosis. In the present study, we have evaluated whether the inducible NO synthase (iNOS) isoform participates in the enhanced renal and systemic NO production of a rat model of cirrhosis.

Intron 4 polymorphism of the endothelial

Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with elevated blood pressure in type 2 diabetic patients with coronary heart disease

✍ Arto Pulkkinen; Laura Viitanen; Anu Kareinen; Seppo Lehto; Ilkka Vauhkonen; Mark 📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 78 KB

High-density lipoprotein administration

High-density lipoprotein administration attenuates liver proinflammatory response, restores liver endothelial nitric oxide synthase activity, and lowers portal pressure in cirrhotic rats

✍ Dominique Thabut; Khalid A. Tazi; Dominique Bonnefont-Rousselot; Maria Aller; Ol 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 781 KB

In patients with cirrhosis, endotoxic shock is a major complication of portal hypertension, which is related partly to intrahepatic endothelial nitric oxide synthase (eNOS) down-regulation. High-density lipoproteins (HDLs), whose plasma levels are reduced in cirrhosis, have an anti-inflammatory effe

Inhibition of inducible nitric oxide syn

Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in murine macrophage cells

✍ Sung-Jin Lee; Ik-Soo Lee; Woongchon Mar 📂 Article 📅 2003 🏛 Springer 🌐 English ⚖ 992 KB