Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in murine macrophage cells

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces senescence-like terminal S-phase arrest in human hepatoma and breast cancer cells

✍ Shutao Yin; Yinhui Dong; Jinhua Li; Junxuan Lü; Hongbo Hu 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 593 KB

Senescence is a permanent growth arrest and has been implicated as an efficient anti-carcinogenesis mechanism. The purpose of this study was designed to test the hypothesis that penta-1,2,3,4,6-O-galloyl-beta-D-glucose (PGG), a naturally occurring polyphonolic gallotannin compound, might induce this