2,4-Dioxo-3,3-dialkyl-6-alkyl(aryl und aralkyl)-piperidine
✍ Scribed by A. H. Lutz; O. Schinder
- Publisher
- John Wiley and Sons
- Year
- 1956
- Tongue
- German
- Weight
- 351 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
The action of metal‐organic compounds upon 2,4‐diketo‐3, 3‐dialkyl tetrahydropyridines leads to the formation of 3,3,6‐tri‐substituted 2,4‐diketo piperidines, the new organic residue being introduced into the 6‐position.
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## Abstract 1‐(Aralkyl/aryl)‐3‐(alkyyaralkyl)‐5‐aroyl‐1,2,3,4‐tetrahydropyrimidines (**2a‐c**) have been synthesized by dethiomethylation of 5‐aroyl‐6‐methylthio‐1,2,3,4‐tetrahydropyrimidines (**1a‐c**). An alternative one‐pot synthetic strategy has been developed for the title compounds **2a‐t** b