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24 Calcium-dependent activation of NF-κB by the adipokine resistin in hepatic stellate cells


Book ID
117373536
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
121 KB
Volume
42
Category
Article
ISSN
0168-8278

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The hepatic stellate cell (HSC), following a fibrogenic stimulus, is transformed from a quiescent to an activated cell. Cytokines induce NFB activity in activated but not in quiescent HSCs with subsequent expression of NFBresponsive genes, such as intercellular adhesion molecule (ICAM)-1 and interle