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2(3H)- and 2(5H)-Furanones. III. An Efficient Synthesis and the Eschenmoser-Mannich Reaction of N-Substituted 4-Amino-2(5H)-furanones

✍ Scribed by Momose, Takefumi; Toyooka, Naoki; Nishi, Takafumi; Takeuchi, Yumi

Book ID
124052267
Publisher
Japan Institute of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
491 KB
Volume
27
Category
Article
ISSN
0385-5414

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πŸ“œ SIMILAR VOLUMES

An efficient synthesis of highly optical
An efficient synthesis of highly optically active 4-substituted-2(5H)-furanones from chiral 3-bromo-2(5H)-furanone
✍ Xue-E Fan; Min Huang; Hui Huang; Qing-Hua Chen πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 662 KB

## Abstract Highly optically active 4‐substituted‐2(5__H__)‐furanones 6a‐6j were obtained in good yields with __de__β©Ύ98% by the tandem Michael addition/elimination reaction of chiral 3‐bromo‐2(5__H__)‐furanone (4a), which was conveniently prepared starting from 2‐furaldehyde under mild conditions.