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2,3,7,8-tetrachlorodibenzo-p-dioxin Causes Increases in Expression of c-erb-A and Levels of Protein-tyrosine Kinases in Selected Tissues of Responsive Mouse Strains

โœ Scribed by David W. Bombick, Jerzy Jankun, Kathryn Tullis and Fumio Matsumura


Book ID
123635588
Publisher
National Academy of Sciences
Year
1988
Tongue
English
Weight
887 KB
Volume
85
Category
Article
ISSN
0027-8424

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2,3,7,8-Tetrachlorodibenzo-p-dioxin caus
โœ Bombick, David W. ;Matsumura, Fumio ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 817 KB

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been found to cause increases in cellular levels of pp6OSrc, a protein tyrosine kinase in hepatocytes from the rat and guinea pig, in the thymus of the mouse in vivo and in NIH-3T3 mouse fibroblast cell lines in vitro. Such cellular changes take place i