Ah receptor involvement in mediation of
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Ryu, Byung-Woo ;Roy, Shukla ;Sparrow, Barney R. ;Selivonchick, Daniel P. ;Schaup
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Article
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1995
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John Wiley and Sons
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English
β 760 KB
The arylhydrocarbon receptor (AhR) plays a central role in mediating 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity in animals. The investigations described here provide evidence that support a role for the AhR in TCDD-mediated pyruvate carboxylase (PC) level/activity reductions in mice. Pyruva