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2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor

โœ Scribed by Toshiko Yamada-Okabe; Takeshi Aono; Haruya Sakai; Yuji Kashima; Hisafumi Yamada-Okabe


Book ID
113923187
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
435 KB
Volume
194
Category
Article
ISSN
0041-008X

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2,3,7,8-Tetrachlorodibenzo-p-dioxin rece
โœ Linda K. Durrin; Phillip B. C. Jones; Joan M. Fisher; Donna R. Galeazzi; James P ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 534 KB

The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dioxin, produces a diverse set of biological responses which, in some cases, reflects the altered expression of specific genes. An intracellular receptor protein binds TCDD saturably and with high affinity and mediates several