2,3,5,6-Tetramethylmorpholine. IV. The observation of a new cyclization mechanism
β Scribed by Sven Hernestam
- Book ID
- 112125792
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1979
- Tongue
- English
- Weight
- 186 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-152X
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## Abstract The structures of the six isomers of 2,3,5,6βtetramethylβmorpholine have been determined by means of proton nuclear magnetic resonance studies at 100 MHz. The spectra have been analysed in terms of spinβspin coupling constants and population distributions of the possible conformers at l
The vanadium(V)-catalyzed oxidation of bromide in the presence of methyl (E)-2-(1-hydroxy-1-methylethyl)-5-phenyl-4-hexenoate furnished 5,6-trans-5-bromo-6-phenyl-2,2,6-trimethyl-3-methyloxycarbonyltetrahydropyran, which was converted into the marine natural product aplysiapyranoid A and its 5-epime