2,3-Butanedione monoxime (BDM) as a myosin inhibitor
โ Scribed by E. Michael Ostap
- Book ID
- 110413719
- Publisher
- Springer Netherlands
- Year
- 2002
- Tongue
- English
- Weight
- 113 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0142-4319
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๐ SIMILAR VOLUMES
## Abstract We investigated the role of myosin in polymorphonuclear leucocyte (PMN) shape changes, locomotion, and fluid pinocytosis using the myosin inhibitor 2,3 butanedione monoxime (BDM). Treatment of resting spherical PMNs with BDM produced spheroid cells showing small continuous shape changes
The growth of fission yeast cultures was reversibly inhibited by exposure to the myosin-ATPase inhibitor 2,3-butanedione-2-monoxime (BDM). Wild-type cells treated with 20 mM BDM for approximately two generation times were smaller than untreated controls and had a septation index approximately twice