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227 Design of high affinity interleukin-6 and gp130 variants: Implications for cytokine-receptor assembly

✍ Scribed by Nina Adam; Stephanie Tenhumberg; Georg H. Waetzig; Athena Chalaris; Björn Rabe; Jan Suthaus; Dirk Seegert; Jürgen Scheller; Stefan Rose-John; Joachim Grötzinger

Book ID
116398514
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
45 KB
Volume
43
Category
Article
ISSN
1043-4666

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Separate regulation of a membrane protei
Separate regulation of a membrane protein, gp130, present in receptor complex specific for interleukin-6 and other functionally related cytokines
✍ András Falus; Judit Biró; Éva Rákász; Thomas Brunner; Stephan Bischoff 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 509 KB

## Abstract In addition to specific ligand binding elements, receptor assembly for interleukin(IL)‐6, oncostatin‐M, leukaemia inhibitory factor, ciliary neurotrophic factor and IL‐11 includes and additional unit, gp130. This molecule is a transmembrane glycoprotein of 130 kDa. In this paper, review