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226. Interaction of boron trichloride with optically active alcohols and ethers

โœ Scribed by Gerrard, W. ;Lappert, M. F.


Book ID
111858755
Publisher
The Royal Society of Chemistry
Year
1951
Weight
538 KB
Category
Article
ISSN
0368-1769

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Asymmetric reduction of ketoxime ethers
โœ John T. Dougherty; Joseph R. Flisak; Jerome Hayes; Ivan Lantos; Li Liu; Lynn Tuc ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 183 KB

The asymmetric reduction of ketoxime ethers to yield enantiomerically enriched chiral hydroxylamines with reagents prepared from borane and norephedrine has been investigated. Very high enantioselectivity (ca. 99% ee) was obtained in the reduction of ketoxime O-(o-nitrobenzyl) ether to O-(o-nitroben