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222 MIR-124 TARGETS ANDROGEN RECEPTOR AND INHIBITS TUMORIGENESIS OF PROSTATE CANCER CELLS

✍ Scribed by Shi, Xu-Bao; Xue, Lingru; deVere White, Ralph

Book ID
118485002
Publisher
Lippincott Williams and Wilkins
Year
2012
Tongue
English
Weight
50 KB
Volume
187
Category
Article
ISSN
0022-5347

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## Abstract Androgen receptor (__AR__) is a ligand‐dependent transcription factor, which plays a significant role in prostate carcinogenesis. Blockade of __AR__ and its ligand, androgen is the basis for the treatment of prostate cancer (PCa). Nevertheless, a modest increase in the critical levels o