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2,2′-carbonyl-bis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine): II-reagent for the direct esterification of carboxylic acids.

✍ Scribed by Denis Grenouillat; Jean-Pierre Senet; Gérard Sennyey

Publisher: Elsevier Science
Year: 1987
Tongue: French
Weight: 119 KB
Volume: 28
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)81065-0

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✦ Synopsis

Reaction of carboxylic acids including N-protected a-amino acids with 2,2 f-carbonyl bis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine) and alcohols affords the corresponding esters under mild conditions.

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