2186 A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brain stem glioma
โ Scribed by SC Dutton; SL Pomeroy; AL Billett; P Barnes; C Kuhlman; NE Riese; L Goumnerova; RM Scott; CN Coleman; NJ Tarbell
- Book ID
- 108435897
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 120 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0360-3016
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## Background: Diffuse pontine gliomas remain one of the most lethal of pediatric malignancies despite the use of increasingly intensive therapies. we delivered intensive chemotherapy during and following 70.2 gy of hyperfractionated radiation therapy in an attempt to improve survival. ## Procedur
## BACKGROUND. Prognosis for the majority of children with brain stem gliomas is dismal. In previous studies, recombinant beta-interferon (@IF) has been shown to be effective for children with recurrent brain stem gliomas and may also act synergistically with radiotherapy (RT). ## METHODS. Thir