2-Thienyl analogues of ephedrine and ?-ephedrine
โ Scribed by Barker, J. M.; Byron, D. J.; Huddleston, P. R.
- Book ID
- 119994558
- Publisher
- The Royal Society of Chemistry
- Year
- 1969
- Tongue
- English
- Weight
- 357 KB
- Volume
- 0
- Category
- Article
- ISSN
- 0022-4952
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The stereoselective syntheses of thienyl and furyl analogues of ephedrine starting from (R)-and (S)-cyanohydrins, respectively, are described. Addition of methyl Grignard to the O-trimethylsilyl protected optically active cyanohydrins (R)-and (S)-3 and hydrogenation of the resulting imino intermedia
Enzyme-Catalyzed Reactions. Part 27. Stereoselective Synthesis of Thienyl and Furyl Analogues of Ephedrine. -Title compounds of type (VII), potential vasodilators and bronchodilators, are stereoselectively prepared from enantiopure cyanohydrins (I). The latter are accessible by oxynitrilase catalyz