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(2′-O-Methyl-RNA)-3′-PNA Chimeras: A New Class of Mixed Backbone Oligonucleotide Analogues with High Binding Affinity to RNA.

✍ Scribed by Beate Greiner; Gerhard Breipohl; Eugen Uhlmann


Book ID
101933727
Publisher
John Wiley and Sons
Year
2003
Weight
53 KB
Volume
34
Category
Article
ISSN
0931-7597

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(2′-O-Methyl-RNA)-3′-PNA Chimeras: A New
✍ Beate Greiner; Gerhard Breipohl; Eugen Uhlmann 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 96 KB 👁 1 views

Dedicated to Prof. Dr. Dr. h.c. Wolfgang Pfleiderer on the occasion of his 75th birthday The automated on-line synthesis of DNA-3'-PNA chimeras 1 ± 4 and (2'-O-methyl-RNA)-3'-PNA chimeras 5 ± 8 is described, in which the 3'-terminal part of the oligonucleotide is linked to the N-terminal part of th