Synthesis of a series of 2 0 -O-[2-[(N,N-dialkylamino)oxy]ethyl]-modified 5-methyluridine nucleoside phosphoramidites and solid supports are described. Using these monomers, modified oligonucleotides containing phosphodiester linkages were synthesized in high yields. These modified oligonucleotides
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2‘- O -[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2‘- O -[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA †
✍ Scribed by Prakash, Thazha P.; Manoharan, Muthiah; Kawasaki, Andrew M.; Fraser, Allister S.; Lesnik, Elena A.; Sioufi, Namir; Leeds, Janet M.; Teplova, Marianna; Egli, Martin
- Book ID
- 127002275
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 166 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0006-2960
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