## Abstract 2‐Methoxyestradiol (2ME) is an endogenous metabolite with estrogen receptor‐independent anti‐tumor activity. The current study seeks to determine the mechanism of anti‐tumor activity of 2ME on human chondrosarcoma. 2ME caused a time‐ and dose‐dependent cytotoxity in chondrosarcoma cells
2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells
✍ Scribed by A Maran; M Zhang; A.M Kennedy; J.D Sibonga; D.J Rickard; T.C Spelsberg; R.T Turner
- Book ID
- 117807559
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 260 KB
- Volume
- 30
- Category
- Article
- ISSN
- 8756-3282
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## Abstract Osteosarcoma is a bone tumor that frequently develops during adolescence. 2‐Methoxyestradiol (2‐ME), a naturally occurring metabolite of 17β‐estradiol, induces cell cycle arrest and cell death in human osteosarcoma cells. To investigate whether the osteoprotegrin (OPG) protein plays a r
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## Abstract The article to which this erratum refers was published in J. Cell. Biochem. 104: 1937–1945, 2008. © 2008 Wiley‐Liss, Inc.