2-Methoxyestradiol, a Promising Anticancer Agent
β Scribed by Nehal J. Lakhani; Mohamadi A. Sarkar; Jurgen Venitz; William D. Figg
- Book ID
- 115048718
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 66 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0277-0008
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π SIMILAR VOLUMES
## Abstract Flavonoids are polyphenolic compounds that are ubiquitously in plants. They have been shown to possess a variety of biological activities at nontoxic concentrations in organisms. The role of dietary flavonoids in cancer prevention is widely discussed. Compelling data from laboratory stu
The aim of this study was to characterize the metabolic pathways of 2methoxyestradiol (2ME2), an investigational anticancer drug. In vitro metabolism studies were performed by incubation of 2ME2 with human liver microsomes under various conditions and metabolite identification was performed using li