2-[Hydroxy(2-pyridyl)methyl]-2-cyclopenten-1-one: the Baylis–Hillman adduct of 2-pyridinecarboxaldehyde and 2-cyclopenten-1-one
✍ Scribed by Huo, Fangjun ;Yin, Caixia ;Guo, Wei ;Xia, Chizhong
- Publisher
- International Union of Crystallography
- Year
- 2004
- Tongue
- English
- Weight
- 379 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
A view of the molecular structure of (I) with the atom-numbering scheme. Displacement ellipsoids are drawn at the 50% probability level and H atoms are shown as small spheres of arbitrary radii.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 298 K Mean '(C±C) = 0.004 A Ê R factor = 0.056 wR factor = 0.146 Data-to-parameter ratio = 12.8 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
Addition of molecular fluorine to cis-2-cyclopentene-1 ,Cdiol gave the c&anti adduct stereoselectively. This meso diol was dissymmetrized by means of acetylation under lipase catalysis to afford the monoacetate with a high enatiomeric purity. Oxidation of the monoacetate followed by elimination of h