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2-Fluoromethyl-4,4,6-trimetiiyl-1,3-oxasine as a new reagent for the preparation of α-fluoroaldehydes

✍ Scribed by Timothy B Patrick; Sedigheh Hosseini; Satinder Bains

No coin nor oath required. For personal study only.

✦ Synopsis

The title compound easily forms an anion on treatment with nbutyllithium.

The anion reacts with electrophiles such as alkyl halides, aldehydes, and ketones.

The resulting products furnish a-fluoroaldehydes after reduction and hydrolysis. ' ~-~ c 2) Electrophile (R) F 1

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