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2-Deoxy-d-glucose protects neural progenitor cells against oxidative stress through the activation of AMP-activated protein kinase

โœ Scribed by Mikyung Park; Kwan Sung Song; Hyun Kyu Kim; Young Joo Park; Hyung Sik Kim; Min In Bae; Jaewon Lee


Book ID
116770999
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
781 KB
Volume
449
Category
Article
ISSN
0304-3940

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Food restriction can extend life span in rodents and was recently reported to increase the resistance of neurons in the brain to excitotoxic and metabolic insults. In principle, administration to ad libitum fed rodents of an agent that reduces glucose availability to cells should mimick certain aspe